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BPS BPS-Pharmacotherapy Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Patient-Centered Pharmacotherapy | 65% | - Adverse drug reactions and interactions - Pharmacokinetics and pharmacodynamics - Therapeutic guidelines and evidence-based treatment - Drug selection, dosing, and monitoring - Pathophysiology and clinical presentation |
| Topic 2: Healthcare Systems and Population Health | 10% | - Regulatory and economic considerations - Medication safety and quality improvement - Population-based pharmacotherapy - Healthcare delivery models |
| Topic 3: Application of Evidence to Practice and Education | 25% | - Drug information and communication - Patient education and counseling - Literature evaluation and biostatistics - Clinical research and guideline development |
BPS Pharmacotherapy (Part1 and Part2) Sample Questions:
1. Which is the most effective method to improve the safety of the use of phytonadione in an institution with a 24-hour pharmacy?
A) Establishment of emergency preparedness kits containing phytonadione to be stored in the patient care areas where warfarin is used
B) Removal of phytonadione from all patient care areas of the facility coupled with strict usage guidelines
C) Computer order sets that default to using a standardized number of vials or amps of phytonadione per dose
D) Yearly in-service education and medical staff presentation about phytonadione use
2. A 70-year-old 45-kg patient is admitted to the ICU with a diagnosis of digoxin intoxication. The patient complains of nausea, blurred vision, and fatigue that have been present for 3 days. A cardiac monitor reveals a HR of 42 bpm, an irregular rhythm, and a type second-degree heart block. Current medications include digoxin 0.25 mg and furosemide 40mg for heart failure, both taken daily at 0800. The patient remains adherent to all medications despite nausea, including today's doses. Blood is drawn at 1200 with the following results:
* Potassium: 6.0 mEq/L
* Creatinine: 2.3 mg/dL
* Digoxin: 1.7 ng/mL
Which of the following most appropriately describes the patient's digoxin concentration?
A) A post-distribution digoxin concentration, which indicates significant toxicity
B) Reflects the effect of furosemide on the renal excretion of digoxin
C) A pre-distribution digoxin concentration, which may be misinterpreted
D) A concentration within the desirable range
3. A pharmacotherapy specialist is conducting a pharmacokinetic study of a drug. The pharmacokinetic profile of this drug is best described by a one-compartment model with a mean elimination rate constant of 0.173/h. The standard curve for the assay to be used covers the range of 5-40mcg/mL. Samples are collected shortly after single intravenous bolus drug administration, and at 4 and 8 hours after dosing. Preliminary analysis shows that the 4-hour sample concentration is 25 mcg/mL. In this situation, which of the following statements is correct?
A) Both the initial and 8-hour concentration points are probably outside the range of the standard curve and cannot be reliably measured without diluting the samples.
B) The initial plasma concentration is probably outside the range of the standard curve' it may be possible to dilute the sample and re-assay.
C) All plasma concentrations are probably within the range of the standard curve and can be reliably measured.
D) Both the initial and 8-hour concentration points are probably outside the range of the standard curve but can be reliably quantitated by extrapolating the curve to higher and lower points.
4. A nurse's aide calls the drug information center, tells the pharmacotherapy specialist that she has found a capsule on her client's countertop and asks if the capsule can be identified. There is an imprint on the capsule. Which reference is the most appropriate to identify this capsule?
A) Red Book
B) The Harriet Lane Handbook
C) Micromedex
D) Martindale: The Complete Drug Book
5. A hospital requests a policy and procedure document for the monitoring and reporting of significant adverse drug reactions. Which agency requires a policy for the reporting of adverse drug reactions by hospitals?
A) Food and Drug Administration
B) Joint Commission
C) National Committee for Quality Assurance
D) Institute for Safe medication Practices
Solutions:
| Question # 1 Answer: B | Question # 2 Answer: B | Question # 3 Answer: C | Question # 4 Answer: C | Question # 5 Answer: A |
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