MRCPUK SEND Exam : Endocrinology and Diabetes (Specialty Certificate Examination)

MRCPUK SEND exam
  • Exam Code: SEND
  • Exam Name: Endocrinology and Diabetes (Specialty Certificate Examination)
  • Updated: Aug 02, 2026
  • Q & A: 200 Questions and Answers
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MRCPUK SEND Exam Syllabus Topics:
SectionObjectives
Diabetes Mellitus- Management
  • 1. Oral and injectable therapies
  • 2. Technology and glucose monitoring
  • 3. Insulin therapy
  • 4. Lifestyle interventions
- Complications
  • 1. Acute metabolic emergencies
  • 2. Perioperative and inpatient diabetes management
  • 3. Macrovascular complications
  • 4. Microvascular complications
- Diagnosis and Classification
  • 1. Other specific types of diabetes
  • 2. Gestational diabetes
  • 3. Type 1 diabetes
  • 4. Type 2 diabetes
Thyroid Disorders- Thyroid Disease
  • 1. Thyroid nodules and cancer
  • 2. Hyperthyroidism
  • 3. Hypothyroidism
  • 4. Thyroiditis and special clinical situations
Reproductive Endocrinology- Gonadal Disorders
  • 1. Polycystic ovary syndrome
  • 2. Disorders of puberty and fertility
  • 3. Male hypogonadism
  • 4. Female reproductive endocrinology
Calcium and Bone Metabolism- Parathyroid and Metabolic Bone Disease
  • 1. Disorders of calcium, phosphate and vitamin D metabolism
  • 2. Hyperparathyroidism
  • 3. Osteoporosis
  • 4. Hypoparathyroidism
Pituitary and Hypothalamic Disorders- Pituitary Disease
  • 1. Hypothalamic disorders
  • 2. Pituitary hormone deficiency
  • 3. Pituitary tumors
  • 4. Pituitary hormone excess
General Endocrinology- Integrated Clinical Practice
  • 1. Endocrine hypertension
  • 2. Neuroendocrine disorders
  • 3. Investigation, imaging and interpretation of endocrine tests
  • 4. Genetic endocrine syndromes
Adrenal Disorders- Adrenal Disease
  • 1. Cushing syndrome
  • 2. Pheochromocytoma and adrenal incidentaloma
  • 3. Primary aldosteronism
  • 4. Adrenal insufficiency
MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) Sample Questions:

1. A 28-year-old Asian woman was seen in the joint diabetes-antenatal clinic at 16 weeks' gestation. She gave a history of gestational diabetes during her previous pregnancy. She had a strong family history of diabetes mellitus. She was fit and well, and had no symptoms other than slight early morning sickness.
According to NICE guidance (NG3, February 2015) for management of pregnancy, what is the most appropriate way to screen for gestational diabetes in this woman?

A) oral glucose tolerance test at 24-28 weeks' gestation
B) oral glucose tolerance test as soon as possible
C) 2-h postprandial plasma glucose
D) haemoglobin A1c
E) fasting plasma glucose


2. A 52-year-old woman had been found to have type 2 diabetes mellitus approximately 6
months previously.
Investigations:
haemoglobin A1c50 mmol/mol (20-42)
What is the lifetime risk of her identical twin sister also developing type 2 diabetes mellitus?

A) >60%
B) 40-50%
C) 20-30%
D) <5%
E) 5-10%


3. A 27-year-old woman with type 1 diabetes mellitus was invited to attend a structured education (e.g. DAFNE) coursE.
Which quality of life domain is most affected when a person is found to have type 1 diabetes mellitus?

A) enjoyment of leisure activities
B) sex life
C) working life and work-related opportunities
D) family life
E) freedom to eat as one wishes


4. A 72-year-old man with a 12-year history of type 2 diabetes mellitus was found to have carcinoma of the bladder. He was taking metformin; however, this was stopped because of his deteriorating renal function.
On examination, his weight was 95 kg and his body mass index was 32 kg/m2 (18-25).
Investigations:
serum sodium143 mmol/L (137-144)
serum potassium4.4 mmol/L (3.5-4.9)
serum creatinine175 umol/L (60-110)
estimated glomerular filtration rate (MDRD)27 mL/min/1.73 m2 (>60)
haemoglobin A1c64 mmol/mol (20-42)
What is the most appropriate addition to his medication?

A) gliclazide
B) pioglitazone
C) dapagliflozin
D) liraglutide
E) sitagliptin


5. A 73-year-old man had been attending the diabetes clinic for 6 weeks with an ulcer on his right second metatarsal head. He had been receiving regular podiatry and offloading.
What new feature in the appearance of his foot is most likely to suggest the need to start antibiotics?

A) pain around ulcer
B) tracking sinus
C) ulcer probing to bone
D) skin redness around ulcer
E) increase in ulcer size


Solutions:

Question # 1
Answer: B
Question # 2
Answer: A
Question # 3
Answer: E
Question # 4
Answer: E
Question # 5
Answer: D

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